Blastocyst Culture

After retrieving the egg, we conduct the fertilization process through ICSI or IVF process to develop the embryo, which is then stored in the incubator for further growth. A blastocyst is the advanced development stage of an embryo. There are 50 to 200 cells in a blastocyst, further matured and developed than an embryo on day 3. 

Let’s explore Blastocyst Culture and Transfer in Detail 


Usually, embryos are transferred on Day 3 to the uterus after fertilization, and three to four embryos could be transferred easily. But we can now grow embryos till the blastocyst stage, i.e., till day 5 after fertilization. In this stage, an embryo develops 50 to 200 cells. 

The embryos which survive the important division and development processes to the blastocyst stage are considered the healthiest and strongest ones as they are best for implants. At Baby Science IVF Clinics, we have advanced technologies for blastocyst culture and transfer to improve the pregnancy rate. Embryo selection is the best part of transfer on day 5. Blastocyst transfers have a better implantation rate per day 5 than embryo transfer on day 2 or 3. 

Benefits of Blastocyst Culture

Blastocyst culture needs ideal and healthy laboratory environments because around 45% of eggs can make it to the blastocyst stage after fertilization. Since only the best and healthiest embryos can become blastocysts after the growth and development in the laboratory, the embryologists are more likely to choose the best embryos for transplant.

In natural circumstances, the embryo also takes five days after fertilization to reach the womb and implant. On this day, the uterine lining is almost receptive. Hence, Blastocyst transfer can be more genetic. 

PGD or PGS is required for some couples. Embryo biopsy is also required in the blastocyst stage for blastocyst culture. 

Who is recommended for Blastocyst Culture? 

You should go for blastocyst culture in one or both of these circumstances – 

  • To avoid the risk of multiple pregnancies – In blastocyst culture, a single most effective embryo is likely to be selected for the transplant. Hence, it significantly lowers the risk of carrying multiple children. 
  • If you had failed IVF cycles – If you have had multiple failed IVF cycles with embryo transfers on day 2 or 3, you need to go for blastocyst culture. This procedure helps in improving the chance of pregnancy and provides more details about embryo growth. 

Why Choose Baby Science for Blastocyst Culture? 

  • At Baby Science, we have the best laboratory professionals and doctors. 
  • We use sequential culture media for embryo culture till the days recommended according to the individual situation of each patient. 
  • We use advanced systems for freezing embryos. So, there is no risk of losing anything in the laboratory if fewer embryos needed to be transferred to avoid multiple pregnancies, along with saving additional embryos to transfer later on. 

In The Process Of Fertilization, An Embryo Will Include Around 6 To 10 Cells After Three Days. On The 5th Or 6th Day, This Fertilized Egg Is Called A Blastocyst. On The Third Day, The Number Of Cells Is 8 In An Embryo And It Is Called The Number Of Blastocysts. A Good Quality Blastocyst Includes: • An Interior Cell Mass • An Exterior Cell Mass • A Cavity Filled With Liquid

If You Are Going With Assisted Reproductive Technology (ART) Then There Are Lots Of Chances Of Having Monozygotic Twins. ART Technology Is Like IVF, ICSI Etc. But In The IVF Process, If Blastocysts Transfer On The 5th Or 6th Day Then It Has A Higher Chance Of Having Twins. After Fertilization, When An Embryo Breaks Then It Can Be The Reason For Twins.

Blastocysts Arise On The 5th Or 6th Day Of Embryo Fertilization. Many Times, A Blastocyst Is Unable To Implant In The Endometrium Because Of Only Two Reasons: • The First Reason Is The Quality Of An Embryo. If The Quality Of An Embryo Is Not Good Then It Can’t Be Implanted. • Secondly, If The Endometrium Is Not Responding Enough Then It Can’t Allow An Embryo To Implant.